A transient increase and subsequent sharp decrease of chemo-refractory liver-metastasized uterine cervical small cell carcinoma to autologous formalin-fixed tumor vaccine plus anti-PD-1 antibody セルメディシン株式会社が紹介する自家がんワクチン療法に関する記事や、論文をご覧いただけます。

Clinical Case Reports 2016; 4(7): 687–691.

Tatsu Miyoshi 1, Tatsuji Kataoka 1, Atsuko Asahi 1, Takashi Maruyama 1, Rika Okada 1, Yoji Uemae 2, & Tadao Ohno 2

1. Ginza-Namiki-Dori Clinic, Ginza 4-2-2 First Yayoi Bldg 7F, Chuo-ku, Tokyo 104-0061, Japan

2. Cell-Medicine, Inc., Sengen 2-1-6, Tsukuba Science City, Ibaraki 305-0047, Japan

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Key Clinical Message:

Uterine cervical small cell carcinoma is rare and aggressive with no standardized therapy. A patient bearing the advanced chemo-refractory carcinoma, treated with a tumor vaccine combined with 1 mg/kg of pembrolizumab, showed a transient increase and subsequent sharp decrease of the liver-metastasized lesion to less than half its maximum diameter.