Authors: Toshio Inui and Tadao Ohno*
Journal: World Journal of Surgical Oncology 2012, 10:144.
Published online 2012 July 12. doi: 10.1186/1477-7819-10-144
Abstract: Treatment of hepatocellular carcinoma (HCC) with autologous formalin-fixed tumor vaccine after primary resection has been shown to suppress the recurrence of hepatitis B virus-associated HCC, but the effect of this treatment on hepatitis C virus (HCV)- related disease has not yet been clarified. Here, we report a case of repeat recurrent HCC that was associated with HCV who had endured 29 episodes of HCC recurrence despite a variety of therapy using conventional methods. Finally, treatment with a single course of autologous formalin-fixed tumor vaccine resulted in suppression of potential further re-recurrence of HCC for more than 43 months without any additional treatment.
