Miyoshi T, Kashiwabara T, Asahi A, Kataoka T, Maruyama T, Okada R, Uemae Y, Ohno T. Complete remission of chemo-refractory multiple-metastatic upper tract urothelial carcinoma by autologous formalin-fixed tumor vaccine. Clin Case Reports, 2017;5:1780–1784.
Key Clinical Message:
A patient with chemo-refractory multiple-metastatic upper tract urothelial carcinoma (UTUC) treated by monotherapy with autologous formalin-fixed tumor vaccine (AFTV) resulted in complete remission of the lung and para-aortic lymph node metastases (ongoing >3 years after AFTV). The tumor was immunohistologically negative for PD-L1. AFTV will be an attractive treatment option.