Induction of human autologous cytotoxic T lymphocytes on formalin-fixed and paraffin-embedded tumour sections. セルメディシン株式会社が紹介する自家がんワクチン療法に関する記事や、論文をご覧いただけます。

会社情報

紹介記事・論文

Induction of human autologous cytotoxic T lymphocytes on formalin-fixed and paraffin-embedded tumour sections.

Authors:Liu, S. Q., Saijo, K., Todoroki, T., and Ohno, T

Journal:Nature Medicine, 1, 267-271, 1995.

Abstract:Human autologous tumour-specific cytotoxic T lymphocytes (CTL) were generated from peripheral blood on small formalin-fixed paraffin-embeddedsections of a gastric cancer. The CTL killed live target cells at an effector/target ratio of 1 within 24 hours and showed the same target specificity as those induced on live cancer cells. The killing activity of the CTL lasted for more than four months in culture and was inhibited by antibodies against CD8 and MHC-class I. These results suggest that adoptive immunotherapy of tumours will be possible with CTL induced on a stable source of tumour antigen.

注:弊社は病院やクリニックではなくバイオ企業であるため、症例報告や論文内容のWeb掲載は許容されています。

ご相談は無料です。
お気軽にお問い合わせください。